At any rate, yes. Node connexions are, I'd say, essential for growth relationships, and those involved in clearing karma. The question here is more quantity than quality, so I'll give a smattering:(It's in synastry with me unless specified otherwise)
NNODE conjunct VENUS-KARMA
KARMA conjunct SNODE
(twin flame)
NNODE conjunct ASC
(husband; karmic partner)
SNODE conjunct SUN
(husband / twin flame)
SNODE-SAT-KARMA conjunct MOON-URA
(twin ray)
PLUTO-JUNO-ASC conjunct NNODE
SNODE-MENTOR conjunct SUN
(mother)
SUN conjunct SNODE
MOON-PLUTO conjunct NNODE
(father)
NNODE conjunct MENTOR
MENTOR conjunct NNODE
(best friend since college)
NNODE conjunct SNODE
MOON conjunct NNODE-VESTA
(close friend, husband's ex-girlfriend)
NNODE conjunct SUN
SNODE conjunct VESTA
(ex college fiance, former costar)
SNODE conjunct JUNO-SATURN
NYMPHE-JUNO conjunct SNODE
(former cowriter and costar, instant connexion, intense relationship; catalyst)
VERTEX conjunct SNODE
(occasional cowriter, best friend since college, lost virginity)
VERTEX conjunct NNODE
NNODE conjunct ASC
SNODE conjunct SUN-MERC-MARS-PRIAPUS
(college romance; intense, short-lived, life-changing)
NNODE-DEJANIRA-VERTEX conjunct CHIRON
SUN conjunct NNODE-VESTA
SNODE-NYMPHE-NEP conjunct MOON-URA-MARS
(astral connexion; current costar, romantic interest, multidimensional relationship)
SUN-JUNO-EROS-VENUS-SNODE conjunct NNODE
SNODE conjunct MARS
(former boss a decade ago; remain close friends)
PLUTO conjunct NNODE
NNODE conjunct PRIAPUS
EROS-PSYCHE conjunct SNODE
SNODE-PRIAPUS conjunct SUN
(first creative writing teacher; remains mentor; amazing woman for whom I have great respect; helped me 'find myself')
SNODE conjunct SUN
MERC conjunct SNODE
(astrologer contact; found twin flames around the same time, became friends)
NNODE-SUN-MARS conjunct PSYCHE
(former therapy client)
NNODE conjunct MERC-SCIENTIA-FANATICA
JUPITER conjunct NNODE
(multidimensional relationship; 'soul brother'; scientific research focus; 'kindred spirit')
NNODE conjunct PSYCHE
(former friend turned therapy client which independently resulted in estrangement)
SATURN conjunct NNODE
NNODE-JUNO conjunct DEJANIRA-SAPIENTIA
(partner of the above)
SNODE conjunct MERC
(karmic partner; antagonistic)
NNODE-DEJANIRA-EROS conjunct PSYCHE
SUN-PRIAPUS conjunct NNODE
SNODE conjunct BML
(former costar; backstabbed; ended very badly)
SNODE conjunct MOON
NNODE-MERC conjunct IC
(Ceri! )
DEJANIRA-MOON conjunct SNODE
PRIAPUS conjunct NNODE
(boyfriend of college best friend; helped with relationship)
BML conjunct NNODE
SNODE conjunct NYMPHE
(Lee Pace; actor; created TV character from character biography I gave him years ago)
MARS-NYMPHE conjunct NNODE
NNODE conjunct PSYCHE
(friend, occasional counselling client, fellow sex educator)
SNODE conjunct MARS
MARS conjunct NNODE
NNODE conjunct EROS
(composer for TV series; love his music! Very karmic.)
SNODE conjunct PRIAPUS
DSC conjunct NNODE
VENUS conjunct NNODE
(husband's submissive; becoming a good friend; karmic)
NNODE conjunct MARS
ASC conjunct SNODE
(husband / his submissive; karmic relationship)
VENUS-NNODE conjunct MERC
(niece by marriage; very close)
NNODE conjunct VERTEX
(development partner; professional TV writer; friend)
--
... Hope that gives a wide range. I'd say the birth years range from 1949 to 1987. Male and female. Various interpersonal relationships of different natures.